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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FBXW10 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10517
Official gene symbolFBXW10
Full nameF-box and WD repeat domain containing 10
Aliases,Fbw10,HREP,SM25H2,SM2SH2,
Gene summaryMembers of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM]
LocationChromosome: 17   Locus: 17p12
Gene position18647326 - 18682662  Map Viewer
Gene orientationplus
Gene size35337 bp
Gene sequence
OMIM ID611679