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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IPO8 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10526
Official gene symbolIPO8
Full nameimportin 8
Aliases,FLJ26580,RANBP8,
Gene summaryThe importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 12   Locus: 12p11.21
Gene position30848929 - 30781915  Map Viewer
Gene orientationminus
Gene size67015 bp
Gene sequence
OMIM ID605600