Entrez gene ID | | 1053 |
Official gene symbol | | CEBPE |
Full name | | CCAAT/enhancer binding protein (C/EBP), epsilon |
Aliases | | ,C/EBP-epsilon,CRP1, |
Gene summary | | The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq] |
Location | | Chromosome: 14 Locus: 14q11.2 |
Gene position | | 23588474 - 23586515 Map Viewer |
Gene orientation | | minus |
Gene size | | 1960 bp |
Gene sequence |
| |
OMIM ID | | 600749 |
|