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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DCTN2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10540
Official gene symbolDCTN2
Full namedynactin 2 (p50)
Aliases,DCTN50,DYNAMITIN,RBP50,
Gene summaryThis gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q13.2-q13.3
Gene position57940978 - 57924094  Map Viewer
Gene orientationminus
Gene size16885 bp
Gene sequence
OMIM ID607376