Entrez gene ID | | 10564 |
Official gene symbol | | ARFGEF2 |
Full name | | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
Aliases | | ,BIG2,FLJ23723,PVNH2,dJ1164I10.1, |
Gene summary | | ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq] |
Location | | Chromosome: 20 Locus: 20q13.13 |
Gene position | | 47538275 - 47653230 Map Viewer |
Gene orientation | | plus |
Gene size | | 114956 bp |
Gene sequence |
| |
OMIM ID | | 605371 |