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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ARFGEF2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10564
Official gene symbolARFGEF2
Full nameADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
Aliases,BIG2,FLJ23723,PVNH2,dJ1164I10.1,
Gene summaryADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq]
LocationChromosome: 20   Locus: 20q13.13
Gene position47538275 - 47653230  Map Viewer
Gene orientationplus
Gene size114956 bp
Gene sequence
OMIM ID605371