Entrez gene ID | | 10575 |
Official gene symbol | | CCT4 |
Full name | | chaperonin containing TCP1, subunit 4 (delta) |
Aliases | | ,CCT-DELTA,Cctd,MGC126164,MGC126165,SRB, |
Gene summary | | The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).[supplied by OMIM] |
Location | | Chromosome: 2 Locus: 2p15 |
Gene position | | 62115791 - 62095262 Map Viewer |
Gene orientation | | minus |
Gene size | | 20530 bp |
Gene sequence |
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OMIM ID | | 605142 |
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