Entrez gene ID | | 10578 |
Official gene symbol | | GNLY |
Full name | | granulysin |
Aliases | | ,519,D2S69E,LAG-2,LAG2,NKG5,TLA519, |
Gene summary | | The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2p11.2 |
Gene position | | 85921414 - 85925875 Map Viewer |
Gene orientation | | plus |
Gene size | | 4462 bp |
Gene sequence |
| |
OMIM ID | | 188855 |
|