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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CDC42EP3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10602
Official gene symbolCDC42EP3
Full nameCDC42 effector protein (Rho GTPase binding) 3
Aliases,BORG2,CEP3,FLJ46903,UB1,
Gene summaryCDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. This protein can interact with CDC42, as well as with the ras homolog gene family, member Q (ARHQ/TC10). Expression of this protein in fibroblasts has been shown to induce pseudopodia formation. [provided by RefSeq]
LocationChromosome: 2   Locus: 2p21
Gene position37899326 - 37870743  Map Viewer
Gene orientationminus
Gene size28584 bp
Gene sequence
OMIM ID606133