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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MXD4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10608
Official gene symbolMXD4
Full nameMAX dimerization protein 4
Aliases,MAD4,MST149,MSTP149,bHLHc12,
Gene summaryThis gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. [provided by RefSeq]
LocationChromosome: 4   Locus: 4p16.3
Gene position2263739 - 2249160  Map Viewer
Gene orientationminus
Gene size14580 bp
Gene sequence