Entrez gene ID | | 10612 |
Official gene symbol | | TRIM3 |
Full name | | tripartite motif-containing 3 |
Aliases | | ,BERP,FLJ16135,HAC1,RNF22,RNF97, |
Gene summary | | The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11p15.5 |
Gene position | | 6495205 - 6469843 Map Viewer |
Gene orientation | | minus |
Gene size | | 25363 bp |
Gene sequence |
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OMIM ID | | 605493 |
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