Entrez gene ID | | 10653 |
Official gene symbol | | SPINT2 |
Full name | | serine peptidase inhibitor, Kunitz type, 2 |
Aliases | | ,DIAR3,FLJ45571,HAI-2,HAI2,Kop,PB, |
Gene summary | | This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 19 Locus: 19q13.1 |
Gene position | | 38755098 - 38783254 Map Viewer |
Gene orientation | | plus |
Gene size | | 28157 bp |
Gene sequence |
| |
OMIM ID | | 605124 |
|