Entrez gene ID | | 10716 |
Official gene symbol | | TBR1 |
Full name | | T-box, brain, 1 |
Aliases | | ,MGC141978,TES-56, |
Gene summary | | This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q24 |
Gene position | | 162272620 - 162281573 Map Viewer |
Gene orientation | | plus |
Gene size | | 8954 bp |
Gene sequence |
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OMIM ID | | 604616 |
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