Entrez gene ID | | 10725 |
Official gene symbol | | NFAT5 |
Full name | | nuclear factor of activated T-cells 5, tonicity-responsive |
Aliases | | ,KIAA0827,NF-AT5,NFATL1,NFATZ,OREBP,TONEBP, |
Gene summary | | The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 16 Locus: 16q22.1 |
Gene position | | 69598997 - 69738553 Map Viewer |
Gene orientation | | plus |
Gene size | | 139557 bp |
Gene sequence |
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OMIM ID | | 604708 |