Entrez gene ID | | 10746 |
Official gene symbol | | MAP3K2 |
Full name | | mitogen-activated protein kinase kinase kinase 2 |
Aliases | | ,MEKK2,MEKK2B, |
Gene summary | | The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q14.3 |
Gene position | | 128100770 - 128062139 Map Viewer |
Gene orientation | | minus |
Gene size | | 38632 bp |
Gene sequence |
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OMIM ID | | 609487 |
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