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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MAP3K2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10746
Official gene symbolMAP3K2
Full namemitogen-activated protein kinase kinase kinase 2
Aliases,MEKK2,MEKK2B,
Gene summaryThe protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. [provided by RefSeq]
LocationChromosome: 2   Locus: 2q14.3
Gene position128100770 - 128062139  Map Viewer
Gene orientationminus
Gene size38632 bp
Gene sequence
OMIM ID609487