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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GRAP (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10750
Official gene symbolGRAP
Full nameGRB2-related adaptor protein
Aliases,MGC64880,
Gene summaryThis gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. [provided by RefSeq]
LocationChromosome: 17   Locus: 17p11.2
Gene position18950336 - 18923990  Map Viewer
Gene orientationminus
Gene size26347 bp
Gene sequence
OMIM ID604330