Entrez gene ID | | 10750 |
Official gene symbol | | GRAP |
Full name | | GRB2-related adaptor protein |
Aliases | | ,MGC64880, |
Gene summary | | This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17p11.2 |
Gene position | | 18950336 - 18923990 Map Viewer |
Gene orientation | | minus |
Gene size | | 26347 bp |
Gene sequence |
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OMIM ID | | 604330 |