Entrez gene ID | | 10772 |
Official gene symbol | | SRSF10 |
Full name | | splicing factor, arginine/serine-rich 13A |
Aliases | | ,FUSIP1,FUSIP2,NSSR,SFRS13,SFRS13A,SRp38,SRrp40,TASR,TASR1,TASR2, |
Gene summary | | This gene product is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing. This gene has multiple pseudogenes. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. In addition, transcript variants utilizing alternative polyA sites exist. |
Location | | Chromosome: 1 Locus: 1p36.11 |
Gene position | | 24306953 - 24292935 Map Viewer |
Gene orientation | | minus |
Gene size | | 14019 bp |
Gene sequence |
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OMIM ID | | 605221 |
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