Entrez gene ID | | 10800 |
Official gene symbol | | CYSLTR1 |
Full name | | cysteinyl leukotriene receptor 1 |
Aliases | | ,CYSLT1,CYSLT1R,CYSLTR,HG55,HMTMF81,MGC46139, |
Gene summary | | The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung. [provided by RefSeq] |
Location | | Chromosome: X Locus: Xq13.2-q21.1 |
Gene position | | 77583087 - 77528130 Map Viewer |
Gene orientation | | minus |
Gene size | | 54958 bp |
Gene sequence |
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OMIM ID | | 300201 |
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