Entrez gene ID | | 108017 |
Official gene symbol | | Fxyd4 |
Full name | | FXYD domain-containing ion transport regulator 4 |
Aliases | | 0610008I02Rik,AI267073,Chif,MGC107631 |
Gene summary | | This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. [provided by RefSeq] |
Location | | Chromosome: 6 Locus: 6 F1 |
Gene position | | 117887353 - 117883577 Map Viewer |
Gene orientation | | minus |
Gene size | | 3777 bp |
Gene sequence |
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