Entrez gene ID | | 10850 |
Official gene symbol | | CCL27 |
Full name | | chemokine (C-C motif) ligand 27 |
Aliases | | ,ALP,CTACK,CTAK,ESKINE,ILC,PESKY,SCYA27, |
Gene summary | | This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq] |
Location | | Chromosome: 9 Locus: 9p13 |
Gene position | | 34662689 - 34661893 Map Viewer |
Gene orientation | | minus |
Gene size | | 797 bp |
Gene sequence |
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OMIM ID | | 604833 |