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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for HPSE (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10855
Official gene symbolHPSE
Full nameheparanase
Aliases,HPA,HPR1,HPSE1,HSE1,
Gene summaryHeparan sulfate proteoglycans (HSPGs) are major components of the basement membrane and extracellular matrix. Heparanases, like HSPE, are endoglycosidases that cleave the heparan sulfate side chain of HSPGs to permit the remodeling of the extracellular matrix for cell movement or the release of bioactive molecules from the extracellular matrix or cell surface (summary by McKenzie et al., 2000 [PubMed 11027606]).[supplied by OMIM]
LocationChromosome: 4   Locus: 4q21.3
Gene position84256306 - 84216468  Map Viewer
Gene orientationminus
Gene size39839 bp
Gene sequence
OMIM ID604724