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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for HCST (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 10870 Official gene symbol HCST Full name hematopoietic cell signal transducer Aliases ,DAP10,DKFZP586C1522,KAP10,PIK3AP, Gene summary This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq] Location Chromosome: 19   Locus: 19q13.1 Gene position 36393382 - 36395173  Map Viewer Gene orientation plus Gene size 1792 bp Gene sequence >HCST:8661600..8663391:Length=1792 CTTGACACCAGCAGGGTGACATCCGCTATTGCTACTTCTCTGCTCCCCCACAGTTCCTCT GGACTTCTCTGGACCACAGTCCTCTGCCAGACCCCTGCCAGACCCCAGTCCACCATGATC CATCTGGGTCACATCCTCTTCCTGCTTTTGCTCCCAGGTGAAGCCAGTGGTTACAGGGGA TGGTAGGCAGAGCGTTTGTGAGATGGGTGCTTGGGTGACGTCTGCAGGGACGGGTGATGA AAGTGGGGTTCTTCTCCCTGCACCCCTTCCCTTCTGGGAGATCCATTCTGCTTCAGGGCC TGGGTCCTTGGGGGCGGAAGGGGGTGAGACAGGGAGTTCTGGAGGGGCTGCCTGTTAGCG TCCCCTTCTCATGGCTGGGTCTCTGCTGCCACTTCCAATTTCTTGTCACTCTCCATGTCT CTGGGAGTCCCCTTCCCATGTGGTCCTGTTCCATCTCTCCAGCCTGGAGATTACTTCTCA GGACACTACCTTTCCTTCTCTACACCCTATTTTTTGGTTTGTTTATTTTGAGATGGGGTC TTGCTCTGTTGTCCAGGCTGGAGTGCAGTGGCACAATCACGGCTCACGGCAGCCTTGACT TCCTGGGCTCAGGTGATCCTCCCAGCTCAGCCTCCCGAGTAACTGGGATTACAGGTGTGA ACCAACACTTCCAGCTAATTTTTGTATTTCTTGTAGAGACGAGGTCTCACTATGTTGCCC AGGCTGGTCTCGAACTCCTGGGCTCAAGCGATCTTCCTGCCTCGGCCTCCCAAAGTGCTG GGATGACAGGCGTGAGCCACGGTGCCAGGCTGAGCATTCTGTTTTGTGGACCTTCTCTCC ACCCTCATCCACCTTCTTTCTCTTTCCACAGTGGCTGCAGCTCAGACGACTCCAGGAGAG AGATCATCACTCCCTGCCTTTTACCCTGGCACTTCAGGTATCACTTCCACCCCAGAAGCT TGGCCAGAGGCTCCCAGAACACCCCAGTGGTTCTCCAGGTCACCATCCCACCTCCCGTCC CCAAATCAGAGGATCCGTGTCCTTCTCCGAGTCCCAGAATCAGCGACCCCCAGCCTGTGT TCAGGAGCACCCCGTGTGCCCGCCGCACAGCCCCGAGGGTCCTGGGACACCCCAGCCTCT CTGCATCTGTCTCCCGTTTCATTCCCCAAGCGCAACTCCAAGGAACCTGGGACCCGCCCC CTCGCAGGGGACTTCCTCTCTGCCTGTGGCCAAAGCACAGCCCCAGGACGCAGAGCTTGA GTTGTCTCCCTGTTCCGGCCCCCACTCTCCAGGCTCTTGTTCCGGATGTGGGTCCCTCTC TCTGCCGCTCCTGGCAGGCCTCGTGGCTGCTGATGCGGTGGCATCGCTGCTCATCGTGGG GGCGGTGTTCCTGTGCGCACGCCCACGCCGCAGCCCCGCCCAAGGTGAGGGCGGAGATGG GCGGGGCCTGGAAGGTGTATAGTGTCCCTAGGGAGGGGGTCCCAGGGAGGGGGCCCTTGG GGAAGCCCTGGAGGAGGTGCTGGGGAAACCCTGGGGGAGGTGCCTGGGGGAACCCCTGAG GAAACCCCTGAAGCAGGGGGTCCCCAGGGAAGTGGAGATATGGGTGGTCAAGCTTCATGC TTTCTCTCCCCTATCCCCAGAAGATGGCAAAGTCTACATCAACATGCCAGGCAGGGGCTG ACCCTCCTGCAGCTTGGACCTTTGACTTCTGACCCTCTCATCCTGGATGGTGTGTGGTGG CACAGGAACCCCCGCCCCAACTTTTGGATTGTAATAAAACAATTGAAACACC OMIM ID 604089