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Gene information for ME3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10873
Official gene symbolME3
Full namemalic enzyme 3, NADP(+)-dependent, mitochondrial
Aliases,FLJ34862,
Gene summaryMalic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. This gene encodes a mitochondrial NADP(+)-dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq]
LocationChromosome: 11   Locus: 11cen-q22.3
Gene position86383678 - 86152150  Map Viewer
Gene orientationminus
Gene size231529 bp
Gene sequence
OMIM ID604626