Entrez gene ID | | 10873 |
Official gene symbol | | ME3 |
Full name | | malic enzyme 3, NADP(+)-dependent, mitochondrial |
Aliases | | ,FLJ34862, |
Gene summary | | Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. This gene encodes a mitochondrial NADP(+)-dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11cen-q22.3 |
Gene position | | 86383678 - 86152150 Map Viewer |
Gene orientation | | minus |
Gene size | | 231529 bp |
Gene sequence |
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OMIM ID | | 604626 |
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