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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ACTL7B (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 10880 Official gene symbol ACTL7B Full name actin-like 7B Aliases ,Tact1, Gene summary The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known. [provided by RefSeq] Location Chromosome: 9   Locus: 9q31 Gene position 111618275 - 111616868  Map Viewer Gene orientation minus Gene size 1408 bp Gene sequence >ACTL7B:complement(40781400..40782807):Length=1408 GGGGATCTCATTTCTCCCCAGGGGGCTCTAGGCTGTGGATGTGAGAAGGGGAGCAAGGGA GGCAGATGGCGACAAGGAACAGCCCCATGCCCCTGGGCACGGCTCAGGGTGACCCTGGAG AGGCAGGAACACGGCCCGGCCCTGACGCCAGCCTCCGGGACACAGGTGCGGCCACTCAGC TCAAGATGAAGCCCAGGAAGGTGCACAAGATCAAGGCGGTCATCATCGACCTGGGCTCCC AGTACTGCAAGTGCGGCTACGCGGGAGAGCCGAGGCCCACCTACTTCATCTCCTCCACCG TGGGCAAACGCTGCCCCGAGGCGGCCGACGCTGGCGACACCCGCAAGTGGACTTTAGTGG GCCATGAGCTGCTCAACACGGAGGCGCCTCTCAAGCTGGTGAACCCGCTGAAGCACGGCA TCGTGGTGGACTGGGACTGCGTGCAGGACATCTGGGAGTACATCTTCCGCACCGCCATGA AGATCCTCCCCGAGGAGCACGCTGTGCTGGTCTCCGACCCTCCGCTCAGCCCCAGCAGCA ACCGGGAGAAGTACGCGGAGCTCATGTTTGAGACCTTCGGCATCCCAGCCATGCACGTGA CGTCCCAGTCGTTGCTGTCCATCTACTCCTACGGCAAGACCTCGGGGCTGGTGGTGGAGA GCGGGCACGGCGTCTCGCACGTGGTGCCCATATCCGAGGGCGACGTGCTGCCGGGCCTGA CCAGCCGCGCCGACTACGCTGGGGGTGACCTCACCAACTACCTGATGCAGCTGCTCAATG AGGCGGGCCACGCATTCACGGACGACCACCTGCACATCATAGAGCACATCAAGAAGAAGT GCTGCTATGCGGCCTTCCTGCCCGAGGAGGAGCTGGGCCTGGTCCCGGAGGAGCTGCGCG TGGACTACGAGCTCCCGGACGGCAAACTCATCACTATTGGCCAGGAGCGCTTCCGTTGCT CTGAGATGCTCTTCCAGCCCTCCCTGGCAGGCAGCACCCAGCCGGGCCTCCCGGAGCTCA CAGCTGCCTGCCTGGGCCGCTGCCAGGACACGGGCTTCAAGGAGGAGATGGCCGCCAACG TGCTACTGTGTGGCGGCTGCACTATGCTGGATGGCTTCCCCGAGCGCTTCCAGAGGGAGC TGAGCCTCCTCTGCCCCGGGGACAGCCCTGCAGTGGCTGCCGCTCCTGAGAGGAAGACCT CCGTGTGGACCGGCGGTTCCATCCTGGCCTCCCTGCAGGCCTTCCAACAGCTCTGGGTCA GCAAGGAAGAGTTTGAGGAGCGGGGCAGCGTGGCCATCTACAGCAAGTGCTGAGCCTCGG CATTTCCACAGACAAGGCCTCCAGCACAGATGGCCACAGGCCTCTCTATACACATTTACA GAATTTCACATAAAGGTTTACTCTGAAA OMIM ID 604304