Entrez gene ID | | 10922 |
Official gene symbol | | FASTK |
Full name | | Fas-activated serine/threonine kinase |
Aliases | | ,FAST, |
Gene summary | | The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq] |
Location | | Chromosome: 7 Locus: 7q35 |
Gene position | | 150777951 - 150773708 Map Viewer |
Gene orientation | | minus |
Gene size | | 4244 bp |
Gene sequence |
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OMIM ID | | 606965 |
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