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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CBX1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10951
Official gene symbolCBX1
Full namechromobox homolog 1 (HP1 beta homolog Drosophila )
Aliases,CBX,HP1-BETA,HP1Hs-beta,HP1Hsbeta,M31,MOD1,p25beta,
Gene summaryThis gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q21.32
Gene position46178883 - 46147414  Map Viewer
Gene orientationminus
Gene size31470 bp
Gene sequence
OMIM ID604511