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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MLLT11 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 10962 Official gene symbol MLLT11 Full name myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 Aliases ,AF1Q,RP11-316M1.10, Gene summary The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested. [provided by RefSeq] Location Chromosome: 1   Locus: 1q21 Gene position 151032151 - 151040973  Map Viewer Gene orientation plus Gene size 8823 bp Gene sequence >MLLT11:2520793..2529615:Length=8823 GGCGCACTGCTCCCCTCTGGACTGCGGAGGCACTGCACTGCGCGGGACGTGGGAGGGTGC CTCTGCAGCCCCTCAAGGCCGCCGCCCCTGCGGGGAGAACTGGAGAATGCGGACACCTAG ATGAGGCCCTGGCACCCAAGCTGGGGCCCCCGGAATCTCACGTTCCCTTTACTCGCCAGG CATTTCGGGGCAAAACGAAGCGGAGCCCCCCAAACCCCCAGACCTAACCAAGTTCAGAGA TTCGCAGAAGCACGCCCCCCACCCCAAATTTATTGTGCTCTACCCAAAATGGAATAGGAC TAGGTTTATTTACCCATTGTGAGGGTAGAGAGGCGAGTCTGGAGGAGCAGGGATTGGGAG AAGGGGTGGAAAAATACTCTGATTCTTAAAAATACTTTGTAACCTAAAGTCCTTAAATTG TGGAAGAAAGGAATACTCCTCCTTTCCATTGTAGTCTAGAGTTAAGATTTCAAATCCATA AATTAGAGGACCTAAAATTAGAGGGCAATTAACTGCTCATTCATTGGGCCCCCAGTCAGC ACGGGGGTGCTGGAAGAGATCGGGAATAATAGCGCAGACCAATGAGCCTAGGGAGATGCT TTCATCGTCTCTCCTTCCCTCAAGTGTTCTGGAACCTATCATTTGAATTAGCCGAGTCAG GCAGGAGGGGGCGGGGAATCCTTCCGCCCTTCTTAGGAGGGGCTGCATTGCAGGGGGAGA GTGAACTGACAGACTCAGTCACTGAAGAGGGAAAAGGAGTGAGAAGACAAAGCCGTCAAA GCCCCAACAGCTTTGTATTTCTCCAGCCCGGCGCAGACCCCGGAGCTCCCGAGGCACTCC CTCCATCTTTGGAACACGCCAGTAATTGATTGATAACAGGTAAACCAAACTGAGGGAGGG GGCAGGGGGCTGCAAAGATAGAAGAGCGGCTGCTTATGGTTAGATTGAAAGACCCCACAT GAGGTGGGGGACAGCTGAAGAGGAGAGAAGGGGGCGCTATGAACAATGGGTAGTTATTTC TTCACAGCATCCATGCCTTGTTACCTTATACAGACCATTAATCTCTAACAATTTACTTGT AGTTATTTCTCAGCACCTACCTCATTTCAAGTATCCTTTTCTGTAATTTATTGTCCTGTG TATTTAATATCTTCAGTCTACTTATCTTCCTTTTCAAACCATAATTTGTTTTACCAGCTG TTTAATTTTTAGTCCTACTGTATCTCTCTGTCCTCTACTTCCCTATACTTGCAATTTTTT TCTGTAGTGTTCTATGTTTCTCTGTAGGAGGGAGTTTGGGAGGGGGTTATATGGGATAAT GTTGGGTGTAATCCTGACCTTTCTTTGGATAATCTCTTTCATTCCACCTCGAATCTTTGC TCCAAAGAAAGAGGCAGCCTAGGGTAGGAAAGGTGGGGGCCTCTGTGTTGGAGAACTGCC TGATTCCATAGTGAAATCAGTATAGCCCACAGGAGCTAGGTATGGGGACAGATTCTGGAA AAGAATGATTTGCAGCTCAGTGGAATTGGTGGAGGAATGCTAGTAGGAAAATCCAAGCTC TGACTGAGGCACACATTATGAGATGTCAGAGAGGTTCTGCTCCCCTCTACCACCACCACC ACCTTGTCCTTCCCCCTTCCCCATGGTGGCAGCATGACACAGCAAGGCCCTGTTGAGTAG GCCTTGGATGCCCACAAAGGGTCTGGACAAAGGATATTTGGGCGTGTCTGTGTGGCTCCG AGAGTGTATCTTTCTAATCTATACATTTGCTAATCATGTATCTCTAAGAACAGAGTGATA ATTAGATATTGCCTTTGCCTAAAATACCCGGATAATTTAAAGTGAAGGATAGTGGGAAGC ATTTATTGAACATATATTGTGGTACAAGGCACTGTCAAAACCCTTTAAGTAAATGATACC ATTTAAGATAATGAAAGATGTAAAGATAGATGAAGTAGGGCTGGAGAGCATTTGTGGAGG GGAAGGGGAAGCTAGCCAAAAAAGGATCTTTTGCGAAATTTGGAGTATTTGATAATTAAA TCCATACTATATTAAATCAAAAATGTCATTACTACTTACATTAGTGAATAGCATTTTAAC TTCAATTTTCTGTGTAGTATTACTTTATGTTCTTGACTTGATTTTAATGCCACGTATGTT TGCATGCATGTCTTTCTTGAATGTATTTGGTACCCTGTGTACATGTCTCTGGGTCAATGA CATAGAGATTTTAGGCCTTTTGAGTTAATATTTCATAAAATTTGCTTTAGCTTTTTAAAT TGCAAGATAGCTCTACCAAACACTCAGGGACTGTTTGAGCAGTTTTTTATACATACTCTG GTTGTAAGAAAAGGAGTCAGTTTGTCGAAGAGCTTTTTTTTTTTTCTCAGATTCTAGCTT GCTCTACTGCCCTTTGCTTTTCCCCATTCAGATCACAATTACAGGAACAATCACCTAAAC CACGGAAAATCTATTCTTCAGCAACTAAAAATTCTTTTAAGTTTTGGGAATACTGGTATA GGGTTATATAAAGCTGTTGGCAACTATCCATGTACAACACAAAAAGGGATCAGATTGGGA ATTATGAGATCTGGATTCTATACAAACTGGCTGGAAGTCTTCCCAAGTCATTAATTTCTA AGATGTCTTCTAGTTTTAAAATTCTATGATTTTTTCCCCCCATGATTCTATTTTTTTTTT TTTTTTAAGATGGAGTCTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGTGCAATCTTGGC TCACTGCAACCTCCACCTCCCCAGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGC TGGGATTATAGGCGCCTGCCACCACACCTGGCTAATTTTTGTATTTTTAGTAAAGACGGG GTTTCACTATCTTGGCCAGGCTGGTCTCGAATTCCTGACCTTGTGATCCACCTGCCTCGG CCTCCCAAAGTGCTGAGATTACAGGCGTGTGCCACCGCGCCTGGCCCCATGATTCTATTT TTTAAAGAGCCTATAATGTGGCCTGCATTATACTAAGCTCATTCTGGAGAAGACTTGTCA GGTAGGATAGAGAAAAGAACCCAGCTAGCTGTGAAAATAACTGGTAACAGTAAGAATCCC TGTAGCCACAAGTCCATAACAGTATTGACTCCTAGGTATGCTTCTTAGAATCTCTATAGT CCCAGATTTAAGCAGTGGGTGGTTGGTTAATGGATACAACCATTTTTTGTAGCTCTCTTT CTGCACACGTCTCTGCAAAGTACTATGGAGATTATCAGAGTTGAGTATCATAGGATGATG ACCTCACCTTTCCAACATGCTCCCCGACCCTGCTGCAATCCCGGCATCACCCTCCTTCTA AGCAGCTTCTCTGCTGAGTAATGCTCAGTTCCCAGGGTTTATTTTGGAACTTAAACTAAG AAAAAGAACAACTCAGAATTCACTTTCAACATTAAAAACATCCTAGCCTACCCACTCACC ATTCCTGAAGCCCCCACACTCTCACACATCACTGTGTTCTAGATTAACACTTTCTTTTTC TGCCTTAGTACAGTCATTTCACATTATACTGGAGCATTTTGGAACCTATTTAAGGCCATT ATTTAGGAGTCTCTGGCCTGGTGAGACCCAATAGGGTGTGTTGGAGAAAGGCCTTTTGAA ACTTGGGGTTCTGTTTTTGGAGGTGATAGAATGTTCTTTCTGCTCCTTTGGGAACATTTC AACTAATGCTTCTTTTTTTAATTTTTATTTATTTATTATTATTATTATTGAGACGGAGTC TTGCTCTTTCGCCCAGGCTGGAGTGCAGTGGCGCTATCTCAGCTCACCGCAAGCTCCGCC TCCCAGGTTCGCGCCATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCGCCC ACCACCGCGCCCGGCTTAATATTTGTACTTTTAGTAGAGACGGGGTTTCACCGTGTTAGC CAGGATGGTCTCGATCTCCTGACCTCGTGATCCACCCGCCTCGGCCTCCCAAAGTGCTGG GATTACAGGCGTAAGCCACCACGCCCGACCACAACTAATGCTTCTTGACCCTTGGCTAGT AAGTAGCAGGGTGGAGGCTGTAGGCAGCTCTAATAGTCCTAAAATATCAGGCAGGGCTTG GGTAGAATGAGTAGAGAAAGTGATAGATCCATTAACGCATGGAAGAGTATCTGATTCTGT TAAAATACCTTCTTCCAATCTGAACTTTACTTTAAATCCAAATGGATTTCCAATCCATTT GCTCTCATTATCATCAGTATACTCGAGCACTGGGATCAGAGAAAAGAGATCCCTGTTACA GCATAGGAAAGTTATTTATTTATTTATTTATTATTACTTTTTTTGAGATGGAGTTTCGCT CTTGTTGCCCAGGCTGGAGTGCAATGGCGAGATCTCGGCTCACTGCAACCTCCACCTCCC AGGTTCAAGCAATTTTCCTGCCTCAGCCTCCCAAATAACTGGGATTACAGGCATGCGCCA CCTCGCCTGGCTAATTTTGTATTTTTAATAGAGACAGGATTTCACCATGTTGGTTGGGCT GGTCTTGAACTCCTCACCTCCTGATCTGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTAT AGGCGTAAGCCACTGCACCTGGCTAGGAAAGTTCTTTTAGCACCTAGGTTTTGTTCTGAA GGAGAGGTAGGCTAGAGAGAAATGGATTGTTAAGGCTTACCTGTGGGCTAATATAAGGGA ATGGCAAGGTATTAATTAAATAGTGAGGGAAAGTTAATCAGCAGCCTTGAATGGCTTTGT GTACAAAGCCCACCACTTGTGTACAGAGAAAGTAGATTGGTCTTTACCCTTGGGGAAACT CCTAGGTATGGGGACAGATTCTGGAAAAGAATGATTATTTGCAATTCAGTGGAACTGGTG AGGGAATGCTAATAGGAAAATCCAAGCTCTGACTGAGGCACGCATGGTGAGATGCCAGAG AGCTTCTGCTCCCCTCTACCACCACCTTGTCCTCCCCCTTTCCCCATGGTGGCAGCATGA CACAGCAAGGCCCTGTTGAGTAGGCCTTGGATGCCCACAAAGGGTCTGGACAAAGGATGT TTGGGCGTGTCTGTGTGGCTCCGAGAGAGTGTATCTTTCTAATCTACATATTTGCTAATC ATGTATCTCTAAGAACAGAGTGATAATTAGATATTGCCTTTGCCTAAAATACCTGGATAA TTTAAAATGAAGGATAATGGGAAGCATTTATTGAATATATATTGTGGTACAAGGCACTGT CAACCCTTTAAGTAAATGATACCGTTTAAGATAATGATAGATGTAAAGATAGATGAAGTA GGGGTGGAGAGCATTTGTGGAGGGGAAGGGGAAGCTAGCCAAAAAAGGGGTCTTTTGCAA AATTTGGAGTATTTGATAATTAAATCCATACTATATTAAATCAAAAATTTCATTACTATT TACATTAGTGAATAGCACTTTAACTTCAATTTTCTGTGTAGTCTTATTTTATGTTCTTGA CTTGATTTTAATGCCACATATGCTTGCATGCATGTGTTTCTTGAATGTATTTGGTACCCT GTGTACATGTCTCTGGGTCAATGACATAGAGGTTTTAGGCCTTCTGAGTTAATATTTCAT AACATTTGCTTTAGCTTTTTAAATTGCAAGATAGCTCTGCCAAACCCTCAGGGACTATTT GAGCAGTTTTTTATTCATACTCTGGTTTTAAGACAAGGGGTCAATTTGTCAAAGAGCTTT TTGTTTTTCTCAGATTCTAGCTTGCTCTCTACTGCCCTTTGCTTTTCCCCATTCAGAAGG CAATAAGGCCATCCCTATACATAAAATACATTAACAGTGATCTGTAATCCCAAACTGATG GAGTTAGGTAAAACTCTACAGGGTGTTGGGGGAGATGCTGGAGGAAATAGAGTAGATGAA GCTGAGTAAAAGTTTAAGGAAGTCATCTGCAAGAGGTGAGTTTATAGTAGGATTTAGAAG GCAAGAAGGAAAATAGAAAGCAGAAAAGTCACGGAAGGTCTTTTCACACATACCATGAGC TATTAAACCAAAGTCAGGAGGAAGTCAAGTATTTTTAAGTATAATAGGAGTTTGGGCTAG GGGAACGGGGGTTCCTCTATAGACTTGGAGTTTTTTGTTTGTTTTGTTTTGTCTTTTTGT TTTTTGAGACAGGGTCTCACTCTATTCCCCAGGCTGGAGTGCAGCGGCACAATCTCAGCC CACTGGAACCTCTGCTTCCTAGGCTCAAGTGATTCTCCCACTCAGCCTCCCAAGTAGCTG GGACTACAGGCGTGCACCACCAGGCCCAGCTAATTTTTTGTATTTTTTGTAGACGGAGTT TTGCCATGTTGCCCAGGCAGGTCTGGAACTCCTAGTCTCAAGTCATCCGCCTGCCTTAGC CTCCCAAAGTGCTGGGAATACAGGTGTGAGCCACTGAGCTCTTGAATGGAGTCCTGAAAT GTGGAAAGTCTTTTTTTTAAGACAGAATCTTGCTCTGTTGCCCAGGTTGGAAGGCTCACT GCAACCTCACCCTGCTGGATTCCAGCAATTCTCGTGCCTCAGCCTCCCTAGTAGCTGGGA CCACAGGCACAAACCACCATGCCTGGCTAACATTTTGTATTTTTAGTAGAGGCAGGGTTT CCCCATGTTGGACAGGCTGGTCTCAAACTCCTGGCCTCAAGTGATCCACCCACTCTGCCT CCCAAACTTCTGAGATCACAGGCATGAGCCACCACACCTGGCTGAAATGCGGAAAGTATT TTAAGGTGGAGAATGGAGAGAGTTAAGCAAGACAGGAATGAGCATAACTGTAACAGAGGA TATACCACTGCTGGGAAGAATGGGCTAGATTTTGGAAGGCCTTGAAAATCAGACCCAAGA TCAATTTGATGCAATAGATGGTAAATAAGTCATTCCAAGATGGGAAGTTTAGAAAATAGT AGAAATTCGGCCGGGCGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAAG CAGGCAGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACATGGTGAAACCCCGTC TCTACTAAAAAATACAAAACATTGGCCGGGCGTGGTGGTGGGCACCTGTAGTCCCAGATA CTCGGGAGGCTGAGGCAGGAGAATGGTGTGAGCCCAGGAGGTGGAGCTTGCAGTGAGCCA AGATCGTGCCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCCGTCTCATTGAGAGAA AAAAAAAAAAAAAGTAGAAATTCATAATAAAGGGTTTCTGAAGCTTGTCCAAGGGAACTT GGATTCTCTCCAGAGGCAATTGGGGATGGTGAGTTTCTTTTTTTTCCTCCCCAAATTCCT TTTTACTGGTGGGATTGGAGGATATACAATTTTCTTTCTTTAATAGAAAAAAAAAAAAAA AAGAAATTCCTTTTTACCAGTATGTGGAGTATCTAAGCAAGGAAAGGCCATGGGCCACAA AGAAGTTGCTGTAGCATGAAGACTGACAAGTGGTTTCTTTCTAGGAAGCTATGAGGGACC CTGTGAGTAGCCAGTACAGTTCCTTTCTTTTCTGGAGGATGCCCATCCCAGAACTGGATC TGTCGGAGCTGGAAGGCCTGGGTCTGTCAGATACAGCCACCTACAAGGTCAAAGACAGCA GCGTTGGCAAAATGATCGGGCAAGCAACTGCAGCAGACCAGGAGAAAAACCCTGAAGGTG ATGGCCTCCTTGAGTACAGCACCTTCAACTTCTGGAGAGCTCCCATTGCCAGCATCCACT CCTTCGAACTGGACTTGCTCTAAGGCCAAGACTTCTCTCTCCCATCACCTTGCCCTCATT GTCTTCCCTCTCAAGCCCCTTCCTTTCCACTCCTTTCCCATTTTAATCTTGTTCTCTCCC TACTGTGTTGGTGGTGCTGATGAATCTGCCAGAGTTGAGTTCTATGTATTTATTTATCTA TCTGTCTACTCCATTTCTCTCAAAAGCCCTCAAGTCACAAAGTAAATGGTTCAAGCAATG GAGTACTGGGTCACAGGGATTCCTCCTTTCCCCCCCAAATATTAACTCCAGAAACTAGGC CTGACTGGGGACACCTGAGAGTAGTATAGTAGTGCAAAATGGAAGACTGATTTTTGACTC TATTATAATCAGCTTCAGAGATTCCTTAAACCTTCCTAATTTCCTGCTCCAGGGCAGTAA ACACAAATATTTCTTCAAGGGGTGATGAAAACCTCGGAAGTTTTAATTTGAGGTTATCTG CTACGAAACAGTATTTCTAAAAGGCTAAAGTGATAAGTCTCTTGCTTTTTTTTGATCCTG CTCTTATATTCTTTTTTTTCCTCAGAGAAATCAGGAGGGTAGTTAGAGGTATAAAACAGG AGGAAATATTATGGAAAATGAAAATAGGGAAAATAATTGAATCATTTTAGAAGTAGCTAA TTTCTTTTCTCAAAAGAGTGTCCCTTCTTCACACCTACTCACTTTACAACTTTGCTCCTA ACTGTGGGTTGAAAACTCTAGCTAAAGAAAGTTATCAAATCTTAACATGCATTCCTACTA TTATGATAGTTTTTAAGGTTTCAATTCAATCTTCTGAACGGCATAAGTCCTATTTTAGCC TTACCTCCTGCATTTGCAATACGTAATACTGATCAGTGGGCACAGTTCTTCAGCTACATT GAGACCCTGAAATGAACAATTATATTCTGACTCGACATCTTGTCCCCAATCCTTCCAAAA ATATTGATGGTGATTTGTGCTACCATTTACTCGTTTATTTAATAAAGACATTCAATCCCA GGA OMIM ID 604684