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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TMED10 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10972
Official gene symbolTMED10
Full nametransmembrane emp24-like trafficking protein 10 (yeast)
Aliases,P24(DELTA),S31I125,S31III125,TMP21,Tmp-21-I,
Gene summaryThis gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq]
LocationChromosome: 14   Locus: 14q24.3
Gene position75643349 - 75598171  Map Viewer
Gene orientationminus
Gene size45179 bp
Gene sequence
OMIM ID605406