Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LILRB5 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10990
Official gene symbolLILRB5
Full nameleukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
Aliases,CD85C,LIR-8,LIR8,
Gene summaryThis gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 19   Locus: 19q13.4
Gene position54761167 - 54754270  Map Viewer
Gene orientationminus
Gene size6898 bp
Gene sequence
OMIM ID604814