Entrez gene ID | | 10990 |
Official gene symbol | | LILRB5 |
Full name | | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 |
Aliases | | ,CD85C,LIR-8,LIR8, |
Gene summary | | This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 19 Locus: 19q13.4 |
Gene position | | 54761167 - 54754270 Map Viewer |
Gene orientation | | minus |
Gene size | | 6898 bp |
Gene sequence |
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OMIM ID | | 604814 |
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