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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SLC27A2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID11001
Official gene symbolSLC27A2
Full namesolute carrier family 27 (fatty acid transporter), member 2
Aliases,ACSVL1,FACVL1,FATP2,HsT17226,VLACS,VLCS,hFACVL1,
Gene summaryThe protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 15   Locus: 15q21.2
Gene position50474393 - 50528589  Map Viewer
Gene orientationplus
Gene size54197 bp
Gene sequence
OMIM ID603247