Home

Search

Browse

Statistics

User guide

FAQs

Links

Questions

Contribute

Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LILRB4 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 11006 Official gene symbol LILRB4 Full name leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 Aliases ,CD85K,HM18,ILT3,LILRB5,LIR-5,LIR5, Gene summary This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] Location Chromosome: 19   Locus: 19q13.4 Gene position 55174124 - 55179848  Map Viewer Gene orientation plus Gene size 5725 bp Gene sequence >LILRB4:27442342..27448066:Length=5725 CACTTGTTCAATGATGTACCCCCAGTGTCAGGCGCTTTGCAAACACACGATACATACGGG TTGATGTTTGGTCAAGAGAGGAATTAAGACCAGGCAGACAGCAGGCTGGGATCAGAGAGA CCCCATTTCTGTCTGAAATGTCTGCAGAGAACCTGGTGCCTGCCTCAGCCCTAGCTCTGG GGAAATGAAAGCCAGGCTGGGGTTCAAATGAGGGCAGTTTCCCTTCCTGTGGGCTGCTGA TGGAACAACCCCATGACGAGAAGGACCCAGCCTCCAAGCGGCCACACCCTGTGTGTCTCT TTGTCCTGCCGGCACTGAGGACTCATCCATCTGCACAGCTGGGGCCCCTGGGAGGAGACG CCATGATCCCCACCTTCACGGCTCTGCTCTGCCTCGGTGAGATTTAAAGAGGGGGAGGGG AGACCCGAGTCTTGGAGGAAATTTGCCTCACAGCCAGGCCCTGGTTCTTTAGGAGACTCA AAAATCTCAGGGTAGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGC CGAGGCGGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACC CTGTCTCTACTAAAAATACAAAAAATTAGCCGGGGGTGGTTGCAGGCGCCTGTGGTCCCA GCCACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCAGTGA GCCAAGATCGCACCACCGCACTCCAGCCTGGGTGACAGCGAGACTCCGTCTCAAAAAAAA AAAAAAAAAAAAAAAAAAATCTCAGGGTAAAGAGAGGACCTGCTCAGGCTTCCGGGGCAA ATCCCTCACAGGGAACTCTCTTCCAGGGCTGAGTCTGGGCCCCAGGACCCACATGCAGGC AGGTGAGTCTGTCCCCAGCTGTCCCAGGTCCCTCCTCCTCACTGGGACAAGGGGCCACCC ATGGGCAGCTGGGGGAGGAGACAGCAGTTCTGGGTGACTGATGAGGATGACGGGGGGGTC CTGGGGCTGAGAGCTGGGATCTGAGGGCTGAGGAAGGTCTTGGGATCCAGCCTCTGATTT TCTTCCAGGGCCCCTCCCCAAACCCACCCTCTGGGCTGAGCCAGGCTCTGTGATCAGCTG GGGGAACTCTGTGACCATCTGGTGTCAGGGGACCCTGGAGGCTCGGGAGTACCGTCTGGA TAAAGAGGAAAGCCCAGCACCCTGGGACAGACAGAACCCACTGGAGCCCAAGAACAAGGC CAGATTCTCCATCCCATCCATGACAGAGGACTATGCAGGGAGATACCGCTGTTACTATCG CAGCCCTGTAGGCTGGTCACAGCCCAGTGACCCCCTGGAGCTGGTGATGACAGGTGAGAG GACACTCAGGGGTCCCAGCCCCAGGCTCTGCCCTCAGGAAGGGGGTCAGCTCTCAGGGGC ATCTCCCTCTCACAGCCCAGCCCTGGGGATGATGTGGGAGCCCCATTTAACACGGTGCCT CCTTCTCTCCTAGGAGCCTACAGTAAACCCACCCTTTCAGCCCTGCCGAGTCCTCTTGTG ACCTCAGGAAAGAGCGTGACCCTGCTGTGTCAGTCACGGAGCCCAATGGACACTTTCCTT CTGATCAAGGAGCGGGCAGCCCATCCCCTACTGCATCTGAGATCAGAGCACGGAGCTCAG CAGCACCAGGCTGAATTCCCCATGAGTCCTGTGACCTCAGTGCACGGGGGGACCTACAGG TGCTTCAGCTCACACGGCTTCTCCCACTACCTGCTGTCACACCCCAGTGACCCCCTGGAG CTCATAGTCTCAGGTGAGGCTCCTGACCCTGTCCTCTCTGAGCTCAGTGGCTCCGTTCAT GCCCTGCTGCCAGGAGAGCTCTGGGCAGGGATGGAGGGAGAGGGGCTCAGCCAGTGGGGG ACTCAGCCCTCAGAGGGGAGGAGGACAACAGGGGCCCTCCCAGGCATGCCCATGCTCTTC TCCCTCACCTAGGGTCCAGAAGGTGCCAGGTGGACAGAGAAATGGTCCTTGGGAAGCTGC AGGGCAGATATAGGGAGAGGTTCAATTTGATGTGGAGACCCAAGGGCAACCCCAGACTCT CACCCTCCTCTTGTCCTTCTACCCAGGATCCTTGGAGGATCCCAGGCCCTCACCCACAAG GTCCGTCTCAACAGCTGGTGAGTCTCAGAGGCCTCTGTCCAGAGAGTTTCCAAAGCCCGA GGCCTGTCTCAAGACATGCTCAGTGGATCTAAGTCCTCGTTCCAATTCTCAGCTGGGCTT GCTTCCACGGGTGTGGGAGTCGGGCAGCGACTTGGGAGGCACCACAGGCTCCCAAGGCCC TGAGGCTGGGCTGGTGAGGGGTGAGGGGGTCAAGGCTGAAGGAGATGTTGCGGGGAGAAG CCGAGCTGATGCGGGGAGCAGGGCAGCCCCAGCCCTCACATCCCTGTTCTAACCCAGCAG GCCCTGAGGACCAGCCCCTCATGCCTACAGGGTCAGTCCCCCACAGTGGTGAGTGAGGGG CTCTGAGTGGGAGGTGGGCAGGGTCTAGGGGAGCCAAGGGTGGGTTCTGTCCTAGGTTAA GGCTCCTCTGGAGGTGGTGATGTGGACAGGCCCCTCCCCTGCATGGGCCTCAGTTTCTCC AAGTGTAAAGGAGAGAGGCCTGCGGGTGGGAAAGTTCCTTTCAGCTCTGACTCCCAGCTG TGCCCTCCTGGGAGAGGAGGCCTCCCAGGGAACCTCCCAGACCCGATTCCGCAGGGGCCT GTCCGGTCCCACCTGCAGCAGAGACGGTGACCTGGGGCAGGGGAGGGGAGCAGGGCGGTG GTTCAAGACAGTCAGGCTCTTTCCCTGCAACTCTGGGGCTTGGCTCTGGTGCAGGAACAA GGGCTGCAGCTCAGACTCCCGGGTTTCCTTCCCAGCTCTGCCGCTTCCTGGCTGGAGGGG TCTGGGGCAGGCGATTCCCCTCTCTGAGCCTCAGTTTGTGCATCTGTGAAATGGGTGGAG AGAGGGTGGCAATCTCAGGTTGCACAACTGCTGTGAGGGTTGGAGGTAATGAAAGAAAGA CCCAGCACACACAGTAGGTGCACACACAGTAGGTGTGCACATCAATGACATCATCCCCAT TCCTGATGTCATCACGCCCAAGGTCTGAGAAGGCACTGGGAGGTACTGATCGGGGTCTTG GTGGTCTCCATCCTGCTTCTCTCCCTCCTCCTCTTCCTCCTCCTCCAACACTGGCGTCAG GGAAAACACAGGACATTGGGTAAGTAGGAAATTGGGGGACCCGTGGGCTGATGGAGGGTG GGCTCAGGGCACCAGCCAAAGGGACTCCAGATAGGAGAGGTCATCTTAGAAACTCTGCTC CAGAAATTCCCAGTGAGAAAATCTAGAAAGAAGAAAATGAATGAGGGAGTAATGGAAGTG CTTTATTCTTTCGGTTTTTCTAAACTTAGAAAGTATTTAAAACATCCTTGCAAGTGTATT TTCAGGTTTCCTTTCCTCTTGACTTGCATGTGCAAGGCAGGTGGTTCTAACGTTCCCAGA GCTGAGACTCTGTCCATCTTCCCCCAGCCCAGAGACAGGCTGATTTCCAACGTCCTCCAG GGGCTGCCGAGCCAGAGCCCAAGGACGGGGGCCTACAGAGGAGGTAATTCTGCCCAAAGA CCTCAGACTCCCACCCATCCCAACAGCCACCTCACTGTCCCCTTACACTCCCGTATCCTC CCCCAGGTCCAGCCCAGCTGCTGACGTCCAGGGAGAAAACTTCTGTGAGTGAGAGGCAGA GAAGGTGCACCTGGGGTGGAGCTGGGGGTCCCAAAATTTCAATAGCAATGGGGGCAGGAG CACAGGCTAGGATTGGTCAGGGACTCAGGGAGAAGTGGTCTGAACCCACATTGTGGGACC TCGGGGACATCACAGCCCCTCCCTGCGTTGCAGTGGCACTAATGGGAACAGGGCAGGGAC CAGCAGGAATGAGAGGTCCCAGGGAACCTTCCCAGGAGATGAACCCCTTGCTCTACCCCA GCAGGTGCTGCCGTGAAGAACACACAGCCTGAGGACGGGGTGGAAATGGACACTCGGGTG AGAACCCGCCCCTGTCCCCGGCACCAAAGGCCTCCTGGTGCCAGATCTAATCCTGCAGGA CTTCTCTGTCCTCCTTCCCCCGGCTCTCAGCATCGTCACGGTGGACCCCTCCTTGTCCAG CACGCTGCCTCCTGCCTGCTGGGACCTCACTCTCTCCTGCTGTCCTGGGACCTCATGGGC CTCCTCCCGGGTCCCCTTCCTGCTCCTCATCCTCTGTTTGGCCATCTGGTTGTTAGAGAG CTCCCCAGGCCTCAGGAGGATGACGAATAAATGAACCACTCCAGTCCCCTGGGCTCCCCT TCATTCATTCATCTAGTGAGTGTTCCCAGGGAGCTCACTGTGGATGGGGCTCCCCATGGG AGCTGCAGACACAGCAGGGAGCAAAGCCGCCCCCGCCTCCTGAGCTCACCTCGTGGTGGG AGACAAAATGCAAATAAATGCATCGTGTCCAGGAGTGCAACGTGCTGTAAGGAACATAAA CCAGGTAAAGGGCAGAGAGTGTGGGGCAGTGGGGCCAGTCTGAATGGAAAGGGAGGGCTG TCTGCTCAGCTGTCATCTGAGAAGCCTGGACGGAGAGGGCCACGTGATCCTCTAATGGAC GAGCCCCTGCAGGCAGAGGAAACAGCCGTGCAAAGGCCCCGAGGCAGCAGCGAGCTCTTG CAGGAAGGCCGCGTGAGGCTGCAGCCAAATGGGCAAGGTCAGAGTGAGGAGCAGAGGCCA GAACCACAGGGAGGGAGCGGCCAGACCCTCCACGGCCTTAGGGCGTCCCTGAGATTCCGT CAGGAAAGGGATGTAATCGGATCACCCTGGGAACAGTGGGGAAAATTGACTCCAGGGAGT CAGGAGGATTCAAGGACACCCCCCACCACTGTCTCTCTCCAGCAGAGCCCACACGATGAA GACCCCCAGGCAGTGACGTATGCCAAGGTGAAACACTCCAGACCTAGGAGAGAAATGGCC TCTCCTCCCTCCCCACTGTCTGGGGAATTCCTGGACACAAAGGACAGACAGGCAGAAGAG GACAGACAGATGGACACTGAGGTGAGTCCTTTCCTCTCCAGGCCCCCAGGCCTCCCCCAC CCCCACCACGTTCCTTCCCTCTCACTCTCCCCCGCTGCAGGCTGCTGCATCTGAAGCCCC CCAGGATGTGACCTACGCCCAGCTGCACAGCTTTACCCTCAGACAGAAGGCAACTGAGCC TCCTCCATCCCAGGAAGGGGCCTCTCCAGCTGAGCCCAGTGTCTATGCCACTCTGGCCAT CCACTAATCCAGGGGGGACCCAGACCCCACAAGCCATGGAGACTCAGGACCCCAGAAGGC ATGGAAGCTGCCTCCAGTAGACATCACTGAACCCCAGCCAGCCCAGACCCCTGACACAGA CCACTAGAAGATTCCGGGAACGTTGGGAGTCACCTGATTCTGCAAAGATAAATAATATCC CTGCATTATCAAAATAAAGTAGCAGACCTCTCAATTCACAATGAGTTAACTGATAAAACA AAACAGAAGTCAGACAATGTTTTAAATTGAATGATCATGTAAATATTACACATCAAACCA ATGACATGGGAAAATGGGAGCTTCTAATGAGGACAAACAAAAAATAGAGAAAAATTAATA AAGTCAAAATGTTTATTCTTGAAAA OMIM ID 604821