Home

Search

Browse

Statistics

User guide

FAQs

Links

Questions

Contribute

Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IL24 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 11009 Official gene symbol IL24 Full name interleukin 24 Aliases ,C49A,FISP,IL-24,IL10B,MDA7,Mob-5,ST16,mda-7, Gene summary This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq] Location Chromosome: 1   Locus: 1q32 Gene position 207070788 - 207077484  Map Viewer Gene orientation plus Gene size 6697 bp Gene sequence >IL24:588567..595263:Length=6697 GCTTGCCTGCAAACCTTTACTTCTGAAATGACTTCCACGGCTGGGACGGGAACCTTCCAC CCACAGCTATGCCTCTGATTGGTGAATGGTGAAGGTGCCTGTCTAACTTTTCTGTAAAAA GAACCAGCTGCCTCCAGGCAGCCAGCCCTCAAGCATCACTTACAGGACCAGAGGTGAGCA TGGGGGATTCTTGGTTACTTTTTTTTGAAGGACTAGACCTCTGCTTTATTTGTGAAAAGG GGTCAAGGTGGGGACAGCAGAAGTCAATTTTTTTGAGTGTTGATGTAGGGACAAGACATG ACTGTGATGAGGAGCTGCTTTCGCCAATTTAACACCAAGAAGAATTGAGGCTGCTTGGGA GGAAGGCCAGGAGGAACACGAGACTGAGAGATGAATTTTCAACAGAGGCTGCAAAGCCTG TGGACTTTAGCCAGGTGCGGTGGCTCACACCTGTAATCCCAGAACTTTGGGAGGCTGAGG TGGGCAGATCATTTAAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCTG TCTCTACTAAAAATACAAAAAAAAATTAGTTGGGCATGTGTTTTTGATATTTTCAGATAC AAAAATCCCAGCTACTTGGGCGACTGAGGCATGAGCATCACTTGAACCTGGTAGGCAGAG GTTGCAGTGAGCCGAGATCATGCCACTGCACTCCAGCCTGGGTGACAGACTGAAATTCTG TCAAAAAAAAAAAAAAAAAAAAAAGCCTGTGGAGTTTGAAAGAACAGAATGAAAAGACAT TGAGGGAGATGCTAAAGCATAGCCCCCGTCCCCCGTGACCCATAACCCAGGGGTCGCCGC CTCCCTAGCCCAGGTACCAGCAGAACCGGGTCTTCTCTGGTCTTCCTCCCGGTGTAGGGG TGGGAGGCAGTTTCTTTAGGTGTCAGACCAGTGCCTGCAGTAAGAAAGGTTCTTAAATGA TTGTGTAAAGAAGTACGAAAGAAAGGGAGAAAGTAAGAAAGGGAGGGAGCGAGAGAGGAA AGAAGGAAGAAAGAAAGGTAAGGAGGGAGGGAGGGAGAGAGGGAGGGAAAGGACAAAGGG CAAAGAAGGCAGGGGGAAAGAAATTCTCTGCATCAGTTATAATAAATACATAATGGCGTT AGGTTCCCCAGCTTGGAGGCTCTTCACTCAGTCCTTCCCAACTGGCACTTCAGAGGAAGG CTTTAGAGATGATTCATCTGGAAATCTGATGCCTCTCTCTCATTTGGTTACTAAAAAAAG TGAATTTTTAGACTCAAGAGTGAGTGGTTAGTGGAGGTGGCATAGTCTGTGTGTGACCCT GACCTGCCCTCTGTGCCCCTCCCTGGGACCAGGATTAACCCCTTGCTCCCTTGTGATGAG GAGTGAGGGACAGCCGTCTCCTGGGGAGGAGAAAAAGACCTGCCAGCCTATGTGTGCCTA GTGGCTTCAGGGCAGAACTTGGATAAGCACATGTCTAGTTCAGCTCTTTGTTTTCCTGGG TTTGGGCTCCCCAGACGTGGCACATTAGAACCTCCCATTTCTCCACTCTTCTGGGTCAAA TTCTGACTCGCAGGTTGTAGGCTAGAGAGAACTGCGATGGAGAAGGAGGAGGTGCAGGGC GTGTGGGTGTGGACGGGCAAGGTGGGGAAGAGCAGGTGGACAGATGGCAAGACGAGCGGC CTTAAGTTTGAGGGGCAGAAAGACCCCTGCTTCACCCCCACTGCACCTTAGCAAGGCTGC CGGTTTGCAATAGTCTCAACTTGCCCATTGGAGAGTGCTCGAGATTGGCCCGGGGAGACC CTCGGAGCATTTTCCCAGGGCATGTAACTCTGGGTCAGAGGGCCGGCCTCACAGGCTGCC TCCCTTTCTTTCAGCAGACCCTTCTGCCCTCCTTTGCTGGCGACAGCCTCTCAAATGCAG ATGGTTGTGCTCCCTTGCCTGGGTTTTACCCTGCTTCTCTGGAGCCAGGTATCAGGGGCC CAGGGCCAAGAATTCCACTTTGGGCCCTGCCAAGTGAAGGGGGTTGTTCCCCAGAAACTG TGGGAAGCCTTCTGGGCTGTGAAAGACACTATGGTGAGTAAAGTGCTGTTCTGGACCCAG TCGTGGGGGTTCCTGGGGGCAGTGGGCCAGTGGGGCGAGGGGATGCTATTTTATGATTCT GGAGTCCTTCACAGCTTGCTAATCAGTTTCCAGTTTCCCATATAATAACTCTGTGAGGTC AGAAGGCACCACAAGCCCCATTTACACATGAGGAAATTGGGGCTCAGAAAAAATGTGGGC AGCCTCGAGTGAAATAAGCAGTGCCCAAGGGAAACCATGAAGAGAGCTAGATTCATCCAG GCTTCGTCCCGAATAGAGTCTTCGGCTCTAAATCTGAGAACTGGAATGAGTGGCTGGGCT GTGGAGGAAGCTCCAAGGGCAAGAGGCAGCTCTAGGGTGCAGGCTGTCCTCCCTCACATC CTGCTTCCTCACCACATGGAATATGGAGCCAAAATCCTGCCCATAGTGGTTCTTAAAGCA GATAGGCTTATTTCCTCCCATCTCAAATGACCAGAGGCATCAAACTGCTTCCTTATCAAA TCTATGTTCATGCTCTAAGAATAAGAAGAACTCCTGGGACTCCATTTGCTCCTGGGGGGC CAAGCTTAGTCATTTTCGTGGCTGCAACCTTGTCTCCCCTCCCCATGGGCCAGCTCAGCC CAGTCCTTCCTGGGTCCTCTTTTGGTCCCTCTGGCCTTTGAGATCTCACAGACTAGATAG ATTTAGGGGTCTAGGGAAGCAGCACATATTTGCAGAGTTGGTTTCTATGCTGACCCCTAA CCTGGAGACGTCTTTTCTTTCTGTTTGCCAAGCAAGCTCAGGATAACATCACGAGTGCCC GGCTGCTGCAGCAGGAGGTTCTGCAGAACGTCTCGGTAATCAGACCTCGGGGACACCACC CTCTGTGGGACGGGTCTACTGTGGGTGGGAGTGCAAGGCTTTCTTAGGGGAGGTTGATGA AAGCCCTTCACTTCTTCCCTGGACTGACCTTACACAGGACAGGGCCAGACTGTGAGCCAG GGAAGTCAGTGTCTGGGGTTATTGCTATGTGGTATGTGTGTGCAGTGGTACTGGGAGATG GGGAAGGTGGAGGCTTGTAAACATCTTTCTCCATTTAGCCAGAGAATTATATATTTCTCT TTTACTTGTGTAGGCCCAATAGGCATCTACTTAGGTTCATGTCCTCTCTTCCATTTTCAT CCTTTTCTCTGGGTCCTTTTTCCTGGGTCCTCCTTTGGTCCATCTGGCCTTTGATGTCTC ATAGACTGGATAGATTTAGGGGGTCCAGGGAAGCAGCACATATTTGCAGAGCTGGTTTCT ATGCTGAACCCTAACCTGGAGACATCTTTTCTTTCTGTCATGTGAGCTCATGTGAAGTGA GCTCATGACTTAAAATAATACCTAACAAAAGGATTCATCCTTTCTTTCACCACAATCAGG TAGAGTATGTTATCAAGGATGGGTCACCATCTTCTCATCATCCATCTAGTGGGCACAAAC CTACTGAGCCCTGAGCCCTGAAAGATGTGGCACTTCAGGAGCTTGAGGGGGCTAGAGTGC AATTGCTGTGTCCAAAGATATTAGTTTCTCCTCATTTCTTCTGTTCTCAGTCATTTTCCA GCAAACTCTATATCACCAAGTCCAAGTTCAAGCCCTTTTCAGGGTCCATCACATCCCCAT AGCTGTTAAAGAGGCCATGTGGCATAGAAGAAAGAGAATATTAAGCAGATGGGCAGTCAG GAATCCTGGGAGCTAGGCTGTGTCTGCCACTGATTGACTATGTGAATCGGGCCAGGTCAT TTCTCTCCCTGGGTCTTGGTTCCTCCTCTCAAACAAAGACCTGCTCTCCATGGCCCCTGA AGGCTCCTACAGATCTAAGGTTCATCATCACCTTCTAGAAGATCCCTATCTCTGCTGTGC TTATCTTGCCTTGGGTGGCATGTGGGTTGTTCCTTCAGGGGGTCAGGGTGGGCAGAGGCC TTGGCTCAGCAGTGACCCAGACCTTCCCCAGGATGCTGAGAGCTGTTACCTTGTCCACAC CCTGCTGGAGTTCTACTTGAAAACTGTTTTCAAAAACTACCACAATAGAACAGTTGAAGT CAGGACTCTGAAGTCATTCTCTACTCTGGCCAACAACTTTGTTCTCATCGTGTCACAACT GCAACCCAGTGTGAGTAGCACACGCTCTGGATACTGGCAGCTCTGGGTTCAAGTCTAGGT CTGCTTCCAATCTGCTGGGTGACCCTCTGCAAAGTCCTCCACCTCCCTGGGCTTCAGTTT GTTATCTGTAAAATGGGGATGATCACTCCTGCCTGGCAGGATTGCTGCGAGAATTAAAGG AGGTAGCCCCTTTCACAAGGTGGGAGTTTGGTATTGGTTACCTTGGGGAATGCAGGATTC AGCCCTGGGCTCTCAGGCTTTGGGAGACCCTGTGGCATCAGCAGGAAAACTGAGAGGGAG TTTGCATCTGCTCCTATCTAAAAATTGGCACAACTTCTTTTCCCATGTTATGTAGCAAGA AAATGAGATGTTTTCCATCAGAGACAGTGCACACAGGCGGTTTCTGCTATTCCGGAGAGC ATTCAAACAGGTAAGGCCAAGAGCTGAGAGCTTGCCCATCCAGCAGAATAGACTAGTCTG CACCATCACACGAGGGCGCCTCAGAGACCCAATGCAGAATGTAATGCAGGGGACACCATC AGCTTTGCTCCAAAGCCCCCTGACTTAGCAGGAGCACAGTTATATTTGCAGAAGCATCGT AAACTAAGTGGTCTTTTTTCTTCCAGTTTTCAAGTTAAAGTGCTTCTATATTTCCCTACA AGATGATTTTACGAAAGGAACTTTCCCTGTGTTTTGTAGGTACTTGGGCTGGGCAACTGA AGTCAGAAGAGAGGGAGAAAGAAGGGAGACACCCCACCCCCACCCCCACCCCATACACAT CTGCAGTATTTTCCATGATGCTCAACTGGTCTAGTTGTGAAAAACAATTATGGGAAATTA TTTTTGCTTTTCCAAAATTATGACAACAAAGAAAACCCAAATTTCATCCCCAGCCCCCCT AAAAACATAAATGATTTCGATCACTTTTTTTTTTTTGAGGAAGAGATGCATCAGCTTTTA AATAAATGGTGAAGAGCAATAACATCTGATGGAGAGGGGCCACCTGGGCTCATTTCACCT GTGCAGTGGATTCAGGTGGTGGGCCATATCCATCCCATACTGCAGTTTGTGGTTGCTGTT GTTAGGGGTGCCATATGTCTTTCCCTTGTTCTTTGTCCACTGATATTCACTAGCCTGTTT GTCCTCACCCCTGAAGCAGATAAACACATGTAGATGGAGGAAAAGTGACAGGCAGGTGGG TTCATCAGTGGGCTCATCCCAAAGGTGACCCATCCCTTGGATTGGAGTCAGGTCTATTTT AGGCATGGCAGGTTGGAAGAAAGACTATTCTCATAGCTAACATGGCTGACCTTCAACCCT CTTTTCCCTTTAGTTGGACGTAGAAGCAGCTCTGACCAAAGCCCTTGGGGAAGTGGACAT TCTTCTGACCTGGATGCAGAAATTCTACAAGCTCTGAATGTCTAGACCAGGACCTCCCTC CCCCTGGCACTGGTTTGTTCCCTGTGTCATTTCAAACAGTCTCCCTTCCTATGCTGTTCA CTGGACACTTCACGCCCTTGGCCATGGGTCCCATTCTTGGCCCAGGATTATTGTCAAAGA AGTCATTCTTTAAGCAGCGCCAGTGACAGTCAGGGAAGGTGCCTCTGGATGCTGTGAAGA GTCTACAGAGAAGATTCTTGTATTTATTACAACTCTATTTAATTAATGTCAGTATTTCAA CTGAAGTTCTATTTATTTGTGAGACTGTAAGTTACATGAAGGCAGCAGAATATTGTGCCC CATGCTTCTTTACCCCTCACAATCCTTGCCACAGTGTGGGGCAGTGGATGGGTGCTTAGT AAGTACTTAATAAACTGTGGTGCTTTTTTTGGCCTGTCTTTGGATTGTTAAAAAACAGAG AGGGATGCTTGGATGTAAAACTGAACTTCAGAGCATGAAAATCACACTGTCTTCTGATAT CTGCAGGGACAGAGCATTGGGGTGGGGGTAAGGTGCATCTGTTTGAAAAGTAAACGATAA AATGTGGATTAAAGTGCCCAGCACAAAGCAGATCCTCAATAAACATTTCATTTCCCACCC ACACTCGCCAGCTCACCCCATCATCCCTTTCCCTTGGTGCCCTCCTTTTTTTTTTATCCT AGTCATTCTTCCCTAATCTTCCACTTGAGTGTCAAGCTGACCTTGCTGATGGTGACATTG CACCTGGATGTACTATCCAATCTGTGATGACATTCCCTGCTAATAAAAGACAACATAACT CAAGTCTGGCAGACTTTCTTCTCTATTTCTGGATGAATGCCCAGTGAGACTGTGTTGTAC AGCTAGAAAAGGCCTTCTTCCCAATAGCAAGGCTGTGCATCTAGCCTCAAGCTCTGGCTG AACTTTGTGGTCGACATCAATCTAAAGATACAGTGTCTGACTATAACCTTGTTCCAAAAA CCTAGGCAAAGAGTATATGTAGGAGGTGGGATATCACTTCCATGACATAAGTGCTATTGC AGAGCCGTGGCCACCCAGGAACTCCTGACTGCTTTCC OMIM ID 604136