Entrez gene ID | | 11026 |
Official gene symbol | | LILRA3 |
Full name | | leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 |
Aliases | | ,CD85E,HM31,HM43,ILT6,LIR-4,LIR4,e3, |
Gene summary | | Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades (see LILRA1, MIM 604810). One member of subfamily A (LILRA3) lacks a transmembrane region and is presumed to be a soluble receptor (Borges et al., 1997 [PubMed 9548455]).[supplied by OMIM] |
Location | | Chromosome: 19 Locus: 19q13.4 |
Gene position | | 54804265 - 54799854 Map Viewer |
Gene orientation | | minus |
Gene size | | 4412 bp |
Gene sequence |
| |
OMIM ID | | 604818 |
|