Entrez gene ID | | 11027 |
Official gene symbol | | LILRA2 |
Full name | | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 |
Aliases | | ,CD85H,ILT1,LIR-7,LIR7, |
Gene summary | | Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades. One member of subfamily A (LILRA3; MIM 604818) lacks a transmembrane region and is presumed to be a soluble receptor.[supplied by OMIM] |
Location | | Chromosome: 19 Locus: 19q13.4 |
Gene position | | 55085257 - 55099027 Map Viewer |
Gene orientation | | plus |
Gene size | | 13771 bp |
Gene sequence |
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OMIM ID | | 604812 |
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