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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RIPK3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID11035
Official gene symbolRIPK3
Full namereceptor-interacting serine-threonine kinase 3
Aliases,RIP3,
Gene summaryThe product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq]
LocationChromosome: 14   Locus: 14q11.2
Gene position24809242 - 24805227  Map Viewer
Gene orientationminus
Gene size4016 bp
Gene sequence
OMIM ID605817