Entrez gene ID | | 1107 |
Official gene symbol | | CHD3 |
Full name | | chromodomain helicase DNA binding protein 3 |
Aliases | | ,Mi-2a,Mi2-ALPHA,ZFH, |
Gene summary | | This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17p13.1 |
Gene position | | 7788123 - 7816075 Map Viewer |
Gene orientation | | plus |
Gene size | | 27953 bp |
Gene sequence |
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OMIM ID | | 602120 |
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