Entrez gene ID | | 11095 |
Official gene symbol | | ADAMTS8 |
Full name | | ADAM metallopeptidase with thrombospondin type 1 motif, 8 |
Aliases | | ,ADAM-TS8,FLJ41712,METH2, |
Gene summary | | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11q25 |
Gene position | | 130298539 - 130274818 Map Viewer |
Gene orientation | | minus |
Gene size | | 23722 bp |
Gene sequence |
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OMIM ID | | 605175 |
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