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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ADAMTS8 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID11095
Official gene symbolADAMTS8
Full nameADAM metallopeptidase with thrombospondin type 1 motif, 8
Aliases,ADAM-TS8,FLJ41712,METH2,
Gene summaryThis gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q25
Gene position130298539 - 130274818  Map Viewer
Gene orientationminus
Gene size23722 bp
Gene sequence
OMIM ID605175