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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PTPRT (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID11122
Official gene symbolPTPRT
Full nameprotein tyrosine phosphatase, receptor type, T
Aliases,KIAA0283,RPTPrho,
Gene summaryThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq]
LocationChromosome: 20   Locus: 20q12-q13
Gene position41818557 - 40701392  Map Viewer
Gene orientationminus
Gene size1117166 bp
Gene sequence
OMIM ID608712