Entrez gene ID | | 11152 |
Official gene symbol | | WDR45 |
Full name | | WD repeat domain 45 |
Aliases | | ,JM5,WDRX1,WIPI-4,WIPI4, |
Gene summary | | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined. [provided by RefSeq] |
Location | | Chromosome: X Locus: Xp11.23 |
Gene position | | 48958059 - 48932092 Map Viewer |
Gene orientation | | minus |
Gene size | | 25968 bp |
Gene sequence |
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OMIM ID | | 300526 |
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