Entrez gene ID | | 11156 |
Official gene symbol | | PTP4A3 |
Full name | | protein tyrosine phosphatase type IVA, member 3 |
Aliases | | ,PRL-3,PRL-R,PRL3, |
Gene summary | | The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist. [provided by RefSeq] |
Location | | Chromosome: 8 Locus: 8q24.3 |
Gene position | | 142432007 - 142441620 Map Viewer |
Gene orientation | | plus |
Gene size | | 9614 bp |
Gene sequence |
| |
OMIM ID | | 606449 |
|