Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PTP4A3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID11156
Official gene symbolPTP4A3
Full nameprotein tyrosine phosphatase type IVA, member 3
Aliases,PRL-3,PRL-R,PRL3,
Gene summaryThe protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist. [provided by RefSeq]
LocationChromosome: 8   Locus: 8q24.3
Gene position142432007 - 142441620  Map Viewer
Gene orientationplus
Gene size9614 bp
Gene sequence
OMIM ID606449