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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LZTS1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 11178 Official gene symbol LZTS1 Full name leucine zipper, putative tumor suppressor 1 Aliases ,F37,FEZ1, Gene summary This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer. [provided by RefSeq] Location Chromosome: 8   Locus: 8p22 Gene position 20112803 - 20103676  Map Viewer Gene orientation minus Gene size 9128 bp Gene sequence >LZTS1:complement(7961822..7970949):Length=9128 TGAGGGCTTTGCTATGACCTCAGTCCCCTCACGGAGCCACGACTGCCCCTTGCTGCCACA GCCTTTCCAAGACCCTGCCCGGCCCTGCCCCATCCTCAGCCCCGAGTCACCATGGGCAGC GTCAGTAGCCTCATCTCCGGCCACAGCTTCCACAGCAAGCACTGCCGGGCTTCGCAGTAC AAGCTGCGCAAGTCCTCCCACCTCAAGAAGCTCAACCGGTATTCCGACGGGCTGCTGAGG TTTGGCTTCTCCCAGGACTCCGGTCACGGCAAGTCCAGCTCCAAAATGGGCAAGAGCGAA GACTTCTTCTACATCAAGGTCAGCCAGAAAGCCCGGGGCTCCCATCACCCAGATTACACG GCACTGTCCAGCGGGGATTTAGGGGGCCAGGCTGGGGTGGACTTTGACCCGTCCACACCC CCCAAGCTCATGCCCTTCTCCAATCAGCTAGAAATGGTAAGCGGGGGTCGCTGGCAAGGG TAAGTGGGTTGGAAACGCAGGAGAAAGCAAAATGGGGGTGGAGAGCCTGGGGGTTCAGGG GGAGTGGTGACCTGAGCATTCAGACTCCTCAAAACCAGAGCGGCAGGGGTGCCGGCGGAA GCCTGTGGCCACACCGCAGAGATCAAACGTTTCACAAAGGAATTAGAGCATCGCTCAGTC CCCCTGAAGCAGAAGTCTTGGGTCAGGCCATAAGCAAAGAGCACAGGGGATATGTGAGCT TTCTGGAGTCCCACTGAAATGTAGCTGGATTGTCAACGTAGGATCCAGGCGTTTGCCAAG CCTCGGGAAGGAGAGGGAGCCCTGTTCTCATCTGGAAGCACAGATGAAGAGGATGCAGGC CGGGAGTTAACCGCTTCTCTCCCCGGGAGACTCGTGGGGGTGGGTGCGGTCTTCTCATTT GCTGCCCTGGTGTGCATTAGCTCCTTGTTCAAGCTGCGCCTGGGGGCATCTTTGAATACA GGCTGGAGTTTTGTCATCCATTTACCAGAGATTAGGGCAAAGGAGGCCCAGGCACTGAGA AATCCAGCCCTCACACCAGCTCAAGCCCTCGTGCGTCCCACGAGTGGACACTGAAATCAA TTTTCCTATTCAGTCCTCTGCCCCTTGCCCTGGGGAAATGAATCCCCGGCTTTGATTTAC TAGGAAAGAGCCTCTTATGTTTGCATAGAGCATTCAGCTTTTCAAATTAAGGGGCTTGTA AACTGTGAAGCACTCTACCAGGGAAAATTACAGTTTTAAAAAAGGATCGTGATTTGGAGT GAGCCTCCCAACCCTGTAAGGAGGCCAGGTCCGTGTCCTTGCTCCAGGCTTAATGGAAGA GGCAGTGAACAGGAAGAAGGGATGGACCTAAAGAGGGACAGCAAGCTCGGCCAGCCTGAT GCCCTAACTTGCCCCACACAGAGACCTAGAGCAGGAGCCTCAAGATGGTATTTATCACCT CGGGAGGGCTGGGGCAAGCTGGTGGCAGGTTGCTATTTCATAGAACAAAGTGCCCAAGTC GCCATTAGGGTTTTTCCTTCCTAAGAGAGATGACATTCAGCTGCTTCAAAGCAACAGGCA AGGTCTGCTGAGACAATTGACCAAGAGGGGTGCTGCGTGCGCTCAGAGAGCCCAGACTGG CTCAAGGTCGGCACGCGTGCCTGGGGAGGGAGGGTGCAATGCGCGCGCAGGGGAGGCATG AGTCACCGCGGTCCTTTTCCTCTACAGGGCTCCGAGAAGGGTGCAGTGAGGCCCACAGCC TTCAAGCCTGTGCTGCCACGGTCAGGAGCCATCCTGCACTCCTCCCCGGAGAGTGCCAGC CACCAGCTGCACCCCGCCCCTCCAGACAAGCCCAAGGAGCAGGAGCTGAAGCCTGGCCTG TGCTCTGGGGCGCTGTCAGACTCCGGCCGGAACTCCATGTCCAGCCTGCCCACACACAGC ACCAGCAGCAGCTACCAGCTGGACCCGCTGGTCACACCCGTGGGACCCACAAGCCGTTTT GGGGGCTCCGCCCACAACATCACCCAGGGCATCGTCCTCCAGGACAGCAACATGATGAGC CTGAAGGCTCTGTCCTTCTCCGACGGAGGTAGCAAGCTGGGCCACTCGAACAAGGCAGAC AAGGGCCCCTCGTGTGTCCGCTCCCCCATCTCCACGGACGAGTGCAGCATCCAGGAGCTG GAGCAGAAGCTGTTGGAGAGGGAGGGCGCCCTCCAGAAGCTGCAGCGCAGCTTTGAGGAG AAGGAGCTTGCCTCCAGCCTGGCCTACGAGGAGCGGCCGCGGCGCTGCAGGGACGAGCTG GAGGGCCCGGAGCCCAAAGGCGGCAACAAGCTCAAGCAGGCCTCGCAGAAGAGCCAGCGC GCGCAGCAGGTCCTGCACCTGCAGGTACTGCAGCTTCAGCAGGAGAAGCGGCAGCTCCGG CAGGAGCTCGAGAGCCTCATGAAGGAGCAGGACCTGCTGGAGACCAAGCTCAGGTCCTAC GAGAGGGAGAAGACCAGCTTCGGCCCCGCGCTGGAGGAGACCCAGTGGGAGGTGAGGCCA CACAGGGCTCATGGGTTTGGGTGGTCAGCGGTTTGGCGCCAGTACCCCCCTCTCCTTCTG GTGCCGGCCAATAGCGTGCAAACACAGACCGCGCAGGCAAGCGGGGCTAATGTGCTGGCT TTATCACCCAAAGAAGGGGCTCCCTGCAAACCATGTTGGGGGATCGACTTACATCTGAGC TTCCTCCTGTCCCCACCATCACCCTCATGGCTCCTAGATTTCAGTTTCCCAAGTGAGCCA TTAAATCATGAAGCCGGAAGCCAGATGACCAAGGCCCAGCCAGGCTGTGGGCTGACCTCC CTTCCATCAGCTCCCAGGAGGCTCAGAAGAAGAACAAGCCGTGCCTGAGTTCAGGCGGGG CCAGGGGCCCAAGAGAGCACAGAATGCATTTGTTGCTTTGGAGGGAGGGACTGCACCCAC TAGTAAGAGGGACCCTATTGGTGGCAGGTTTCAGTGATGGAAGTGGCCACTCCTTGCTGA AGTGTAAGTGGAACTTCTATTTGGTGAGCTGAGATGGAAACCTAGGAGAGGAAGTAAAGA GTCCCCCACTCACACACTTACACACTCACACACACTCACTCACCCGGTCACACGTGGAAA TGAGGCATCTGTACCTGACCGTGCTGGAGAACCCCATAACCTCTGCATCTATTAGTGGGA AAGCAGCTTTTCTCACCAGCCTGGTGGTCTGGATGACTCATGGAGTTCAAGCCCATCGTT GAGGCTCTTTACATGCTCGCACCCAGCTTGGTCTGTCCACGTGCCTGCCTCACCCCCAGT TCAGAGTCCAACTCTCAGTCTACACGCAAACCCCTGGCTATGTGCAAGTCAACAACCAGT GGTTTAACTTGCCCACTGCTGGCAGCTGTATCACCCCCATTTAACACCAATGGTATTGGT TTTGGTGTCAGCCTGATTTCCGTCATCGACGTTTATGCCCACATCCTCTGACCTCACCCC TGCATGCACCCAGCCCTCCTCTCTCCTGTCTACTGGAGTAAAGACTACCTCACAAATTCA CTGCTGTACCCAGTGACTAGTATCATGCTGGCTTGGATGCAGAGCCCAATCCACATCTGT CAAACGAGGAATCATTGTCTTCTCCTCTTGCTCTTCTTCTCTATTTCCACCCCTATCCCC CATCAAAATTTGGCCAAGAGCAATGATGAAAACCGAAGCCACAGGTTAGACCCATGTGTC TCTGGATCTTGGCCATCTGGGGTCATGGGAGACCAAGGCCAGTCTGGCTGAATCTTAAGA GTGAATGAAGTCCAGAGCATGTGGCTCTACAGAATGGATTCTTGGAACTAGCCTGGAAGC CACCTTCACATTTCCTTTCACAGTAGAAATTTCCCCTTGCCCTCAGTGAAACACTGCACA GTCCTGGAGAAAATCCGACCCTACCCAGGATGCGTGCTTGGGACCAAGAATTTCATTCCA AGGCCAACCCTGTATTCATGCCACGAAGGGAGTGACACAGTCATGGCTGAGGCATGGGCC TGGCTTTGAACCTCAGCTTGACCACTTATGATCCAGGTGATTGTAAATACATTAGCCATG GTGGCAATGGGGTATAGTGATTAAACTGTTGGGATCAAATCTCTACTCTTATACTTTATA TTTTATATATATATATATATATATATATATATATATATATATATATATATATATTAGCCC TCAGGCTGGTCACTTCACCAGCTATTTGCTATCATAACCTCTCTGTGCCTCAGTTTCATT GATGTAAATTGAGGACTACTAATAGTACCTACTTCATCGGGTTGTAAGGAATAGATGAGC AAATGTATGGCTTGGCACTTAATAACACTACAAATTATTAGTGAAAGTATGTTTATAATA ATATACTTCTGTGTGGCTAGGCGTGGTGGCTCACGCCTGCAATCCCAGCACTTTGGGAGG CAGAGGCAGGCAGAGCACTTGAGGTCAGGAATTCGAGATCAGCCTGGCCAACATGAGGAA ACCCCGTCTCTACTAAAAATACAAAAATCAGCCAGGCATGGTGGCAGGTGTCTGTAATCC CAGCTACTTGGGAGGCTGAGGCAGGAGAATCAGAGGGGAGGCGGAGGTTGCAGTGAGCCA AGATCACGCCACTACACCCCAGCCTAGGTGACAAAGCGAGACTTCTCAAATAATAACAAT AATAATATACTATGTGTCATTATACATGATTATTATTATTTTATCATTTTACTATATAGC CTAGCTCGATAACCTGGGGAAAAGGTCACAGCAATGTTCAGCTTACTTTCAGATTGGACA AAGGCTGGAATGCCTAACACCGGGCCACCGCATCCGGAGTGGCTTGGTTATTTTAGGCAG CTGAGCTGTCACTTCCCTGGGTAAGGACACTCACCTCTTGGCACTCTGTCTCCACCCCAC CCTCGGCAGGTGTGCCAGAAGTCAGGCGAGATCTCCCTCCTGAAGCAGCAGCTGAAGGAG TCCCAGACGGAGGTGAACGCCAAGGCTAGCGAGATCCTGGGTCTCAAGGCACAGCTGAAG GACACGCGGGGCAAGCTGGAGGGCCTGGAGCTGAGGACCCAGGACCTGGAGGGCGCCCTG CGCACCAAGGGCCTGGAGCTGGAGGTCTGTGAGAATGAGCTGCAGCGCAAGAAGAACGAG GCGGAGCTGCTGCGGGAGAAGGTGAACCTGCTGGAGCAGGAGCTGCAGGAGCTGCGGGCC CAGGCCGCCCTGGCCCGCGACATGGGGCCGCCCACCTTCCCCGAGGACGTCCCTGCCCTG CAGCGGGAGCTGGAGCGGCTGCGGGCCGAGCTGCGGGAGGAGCGGCAAGGCCATGACCAG ATGTCCTCGGGCTTCCAGCATGAGCGGCTCGTGTGGAAGGAGGAGAAGGAGAAGGTGATT CAGTACCAGAAACAGCTGCAGCAGAGCTACGTGGCCATGTACCAGCGGAACCAGCGCCTG GAGAAGGCCCTGCAGCAGCTGGCACGTGGGGACAGCGCCGGGGAGCCCTTGGAGGTTGAC CTGGAAGGGGCTGACATCCCCTACGAGGACATCATAGCCACTGAGATCTGAGGGGCTGCC TGGGAAGGCGAGTCTGGGGACCTGGCACTGGGAGGCAGGGCTCTCCCGTGCATCCCCCCT GCTCAGCAATTCAGACCCCTTTGAGAGACGCCACTCCCTGGGACACAGACCCAGGACCCC CGAGGGGAGGGCAGGATGGCCTTTCCTTCCCTCTCTGATGTCCCAGTGCTCACCAGCCCT GCAGCCCACCAGACGTCAGGCCCTGACTCCTCTGGCTTTCCCAGGAGATGGGTCCAGGGG TCTGTCTGCTTTGGTTAAGGGCTCCCTAAACTTTGGCCTTTGTTCGAAATAGATATCCTC TCCCCCTCCTCCAGGGAAGGTGGCCACAGCAAGTACAGCGGCTCCCCTCTGCTTCTCATC CCAACCTCTTTTTCCTCCTGGACACATTGGAATGCCTTGGAAATAGAAAGAAGCCATATA TGACCAGAAGCCTTGGAACCAGCCCCATCAGAACCTGAGCTATTTTCCTCTGGCCGCAGA GGTGTAGGGGTGGAATGAGCCGCGGGGAAGCTGGCTTTGAAACCTCAGGGCTGTCCCAGC CCCGGCAAGCCACAGGAAGGAGGGGAGAGACAGGCAGCCCAGCAGTGTGGAGACCCTGCC ACAGCCAGAGGAGGGCAGAGGGAGAATCCAAGGGTTGAGAGCCAGTGGCGGGTGATGGCC AGCCCCTGGGGCCCAGCCCCTGTTTACTGGTTCTTGCAAATGGGAGCTGAGCAGCCTCTG GACAGCCAGTGACCTTTGACCTCGGTGACCACTCTTCTTTAAGCCATAGACCCTGAGGCC CTGGGCTGGGTGCTGGGAAGGGAGGGTTGAAACCACCGTGAACCAGAGGGTGTGGCTTTC CAGGCACCCTCAGGGAGCCTCCCCATCTGTCCAGCTGGGGCCAGAGGCTGGGAGTCCCTA CCTGCTTCACGTTGGCCGGCGGCTACTCTGGAATGTTTTTCCCTCCCCAGAATCAAGCTT TTGCTTGATCCAGAAGAGCCCATATCACTAAGATGGCATATATGTGATCTGGGCATTTTC CTCCTCTGCCTACAGCCAGGTTTAGCGGCAAACCTTTCCCCCTTAGCACCTTCAGGGCTG AGTTCTGGGTTTCTAGAGGTCAGGACGGCTCCTCAGAGCGCCAGGAAGCCAGAGCCCCAA GCAGGACGAAAAAGAGGCATACACACAGCAGTGTGAATAGCCTGGCCACCAGCCATCCTC CCTCCACCTCAAGACCCCCATTTGTCCCAGACTAAAGGATCCAGAGAGCAGCTCCCTTTC TCAGGAGCTTGGGCAGTGCCCCAGGGAGTCCAGGGTTTCTCTGCAGATGTGCGGAGCGGG AGGCGGTGGTAGAGAGAGATAAAAGGTGGAGTTTCTCTGTTGTTTGGTTCAGGGATTTTA TTTTTAATTTTATGAGACAGGGTCTTGCTCTGTCCCCCAGGCTGGAGTGCAGTGGCATGA TCATAGCTCACTGCAGCCTCATACTCCTGGGCTCAAGCAATCCTCCTGCCTCAGCCTTCC AACTAGCTGGGACTACAGGTGCGCGCCACCGTGCCTGGCTAACTTTTCATTTTTTTTGTA GGGACGGGGTCTCGTTTTGTTGCCAAAGCTGGTCTCAAACTTGTGGCCTCAAGCAATCCA CCTGCCTTGGCCTCCCAAAGTGCTGAGATTGCAGATGTGAGCCACCGTGCCTGGCCAGAT TTTTCTTTTATTCTTCTTTCTTTTTCTTTTTTGCTTTCTTGTCTTTTCAGAAGCAAGCCA GACCTAGCAGGCTGTTCCATGTTCTATTTTTGACTGTAGCCACAGCTGCTGTTCTCAGGA CAGCATCCCTTCCCACATGCCTGCGCCTGCTGCCTGCTGAGATGAGGAGGGGAGCGTCTG GGAACTTGCGAGTCCAAGGCCAGTCCCCATTTCTGCCTCGCTCACCGCTGGCCCTTAGAG ACCCCGAGGTAGGGGTGGGGAGATGCTTCTCTCCTTGCCCCCCGCCCTCATGGGTCCTAG CCCTTCCCTGAGTGCGGGCTGAGGCCAGAGTCACCTTTTCTGTGGCTGGCTCTACCTTCC TGTCCCTGAGGTTAAACGGTGCCCATCCTGCCATCCTCAAACGACAGAGGAGCTTTTCTG GAATTTCAAACCATTGCTCTTAGTCCCAAGCTAGGCTTAAACCTGGAATCTACAAGCCAA AAGTCCCTCCCTGCCTGAGGGCAGTACCCTCCATTGGGCACAGTCCAGACCCAAGTCAAA GATGCCCCATTCCTTGCGCCTCAGCCCTCAGTTCCTTCATTTCCACCAGGCCGTGCCTTG TTTGAGTTTTTCCTCCCAGTGAGACTGCCCCACGGAGACAGAGGAAAGGGCTGGCTCCCC CTCCCCAGGCTGGAGACCCCCCCCCAACTCCAGGAAAGAGCAGTCAGAGTCCAGTGCTCT GCCTCAGACGTTGCCTGAGAAGAAGTGGCTGCCACACCCAGGGGAAGGCCCTGAGGCGGA GGCTGTGCTCCGCCATGGTGTCCCGGTACCTTCCATACACAGAGGAGTGCAGCCTTCTCC ATATCTCCATGGCCCTGTCCCAGGCCGGCCCAGATGTGTCCCCCCCAGGCCTTGTCCTAC GTCCAAGGTGGCAGATGTCTTCCCTGGGCTGCCACCAGCCCCCGCCCCAGAGTGGCCCAC CGTGGCACTAGAATGCAAGTATCCTGCGACCTTGCAACCTCACCTTCCTGTGGGTGTTCT TTCCTGCCCTGTCCAAAAGCGCCCTCACTATTCTTGGACCATGCCAGATTCTGCCTCTCT GGAAAGAGGCTCTGGACAGCAGAAGCCTCCAAGCACAGAGCCTGGCCCCAGGCCCCAGAC AGGGTGGGCTTCCTGCCCTTCCCTCTGGGCACGCCTGCTGGCCGACCCACTGACCCACTC GGATGGACCAACCTGCTCTGTCCCCAAAGGACGCCTGCAGGAGAGAGCAGCACTCCGCAT CACCTCACCAAGGATCGGACTCTGCCCCTGGACCTGGGAACGACTGGACTGTCACGGGGT TCCCTCCTAGCTCTCCCAGTGAACTCCTGCCAGGCACACACAGCCCCTATAGCACTGAGC TCACATGGGACTGGGATATGGGGGCATCTCTTCCCCAGAGAGGCACTCAGTGAGCCTCCT GTGCCTGGCCCCAGCCTGGGCCATCTCTTAGGTGAGACAGTTGCCCGAAACTAAGCCAGG CCTGGCTGGAGGAGCAGCAGCTTGGGGAGAGGGATTTCCCTGCAGACCTCAAGCCATCAT GCGGTGGGTGCTGCCATGACAGAGGCTGCACCCCTGGGCCAGCGGGGCTGCTCACCCACC TCTTGTGCAAGGTGGCCTTTGTGCTGCGCCTGCAGGCAGAGCTGGAGCCCCCAGCAGAGG CAGGCTGGGACGGACCAGCATCTGGAAGATGTACATAGTTATTTTTCTCTTTGTGGTTTC TTGTTTGGTTTGGTTTGCTTTTGACAGCTTCATTTTATTTTTGACGTCACTTTTTGGCCA TGTAAACTATTTGTGGCAATTTTATGTTTTTATTTATGAATAAAGAATGCCATTTCTCAC GCCCTCTA OMIM ID 606551