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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GALNT6 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID11226
Official gene symbolGALNT6
Full nameUDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
Aliases,GALNAC-T6,GalNAcT6,
Gene summaryThis gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q13
Gene position51785200 - 51745833  Map Viewer
Gene orientationminus
Gene size39368 bp
Gene sequence
OMIM ID605148