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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PDCD10 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID11235
Official gene symbolPDCD10
Full nameprogrammed cell death 10
Aliases,CCM3,MGC1212,MGC24477,TFAR15,
Gene summaryThis gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]
LocationChromosome: 3   Locus: 3q26.1
Gene position167452651 - 167401694  Map Viewer
Gene orientationminus
Gene size50958 bp
Gene sequence
OMIM ID609118