Entrez gene ID | | 11238 |
Official gene symbol | | CA5B |
Full name | | carbonic anhydrase VB, mitochondrial |
Aliases | | ,CA-VB,MGC39962, |
Gene summary | | Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles. [provided by RefSeq] |
Location | | Chromosome: X Locus: Xp21.1 |
Gene position | | 15756412 - 15805748 Map Viewer |
Gene orientation | | plus |
Gene size | | 49337 bp |
Gene sequence |
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OMIM ID | | 300230 |
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