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Gene information for CA5B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID11238
Official gene symbolCA5B
Full namecarbonic anhydrase VB, mitochondrial
Aliases,CA-VB,MGC39962,
Gene summary Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles. [provided by RefSeq]
LocationChromosome: X   Locus: Xp21.1
Gene position15756412 - 15805748  Map Viewer
Gene orientationplus
Gene size49337 bp
Gene sequence
OMIM ID300230