Entrez gene ID | | 11279 |
Official gene symbol | | KLF8 |
Full name | | Kruppel-like factor 8 |
Aliases | | ,BKLF3,DKFZp686O08126,MGC138314,ZNF741, |
Gene summary | | This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants. [provided by RefSeq] |
Location | | Chromosome: X Locus: Xp11.21 |
Gene position | | 56258822 - 56314322 Map Viewer |
Gene orientation | | plus |
Gene size | | 55501 bp |
Gene sequence |
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OMIM ID | | 300286 |