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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for POU6F2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID11281
Official gene symbolPOU6F2
Full namePOU class 6 homeobox 2
Aliases,RPF-1,WT5,WTSL,
Gene summaryThis gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
LocationChromosome: 7   Locus: 7p14-p13
Gene position39017609 - 39504390  Map Viewer
Gene orientationplus
Gene size486782 bp
Gene sequence
OMIM ID609062