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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CHRNA3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1136
Official gene symbolCHRNA3
Full namecholinergic receptor, nicotinic, alpha 3
Aliases,LNCR2,MGC104879,NACHRA3,PAOD2,
Gene summaryThis locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq]
LocationChromosome: 15   Locus: 15q24
Gene position78913637 - 78885394  Map Viewer
Gene orientationminus
Gene size28244 bp
Gene sequence
OMIM ID118503