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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TOP1MT (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID116447
Official gene symbolTOP1MT
Full nametopoisomerase (DNA) I, mitochondrial
Aliases,-,
Gene summaryThis gene encodes a mitochondrial DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of DNA which allows the strands to pass through one another and relieves the stress introduced by a circular mitochondrial genome during replication and transcription. [provided by RefSeq]
LocationChromosome: 8   Locus: 8q24.3
Gene position144417050 - 144391526  Map Viewer
Gene orientationminus
Gene size25525 bp
Gene sequence