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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CLNK (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID116449
Official gene symbolCLNK
Full namecytokine-dependent hematopoietic cell linker
Aliases,MGC35197,MIST,
Gene summaryMIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603; BLNK, MIM 604515). MIST plays a role in the regulation of immunoreceptor signaling, including PLC-gamma (PLCG1; MIM 172420)-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell degranulation (Cao et al., 1999 [PubMed 10562326]; Goitsuka et al., 2000, 2001 [PubMed 10744659] [PubMed 11463797]).[supplied by OMIM]
LocationChromosome: 4   Locus: 4p16.1
Gene position10686386 - 10491838  Map Viewer
Gene orientationminus
Gene size194549 bp
Gene sequence
OMIM ID611434