Entrez gene ID | | 116449 |
Official gene symbol | | CLNK |
Full name | | cytokine-dependent hematopoietic cell linker |
Aliases | | ,MGC35197,MIST, |
Gene summary | | MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603; BLNK, MIM 604515). MIST plays a role in the regulation of immunoreceptor signaling, including PLC-gamma (PLCG1; MIM 172420)-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell degranulation (Cao et al., 1999 [PubMed 10562326]; Goitsuka et al., 2000, 2001 [PubMed 10744659] [PubMed 11463797]).[supplied by OMIM] |
Location | | Chromosome: 4 Locus: 4p16.1 |
Gene position | | 10686386 - 10491838 Map Viewer |
Gene orientation | | minus |
Gene size | | 194549 bp |
Gene sequence |
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OMIM ID | | 611434 |
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