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Gene information for ARAP2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID116984
Official gene symbolARAP2
Full nameArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Aliases,CENTD1,FLJ13675,FLJ44916,KIAA0580,PARX,
Gene summaryThe protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. [provided by RefSeq]
LocationChromosome: 4   Locus: 4p14
Gene position36245979 - 36067622  Map Viewer
Gene orientationminus
Gene size178358 bp
Gene sequence
OMIM ID606645