Entrez gene ID | | 116985 |
Official gene symbol | | ARAP1 |
Full name | | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
Aliases | | ,CENTD2,KIAA0782, |
Gene summary | | The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11q13.4 |
Gene position | | 72463434 - 72396114 Map Viewer |
Gene orientation | | minus |
Gene size | | 67321 bp |
Gene sequence |
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OMIM ID | | 606646 |
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